Types of erectile dysfunction medications
Erectile dysfunction medications are typically in the form of a tablet. Other options such as alprostadil and vacuum pumps are available when tablets are unsuitable or don't work.
Erectile dysfunction pills
The main ED tablets belong to a group of medicines called PDE5 inhibitors. PDE5 inhibitors increase blood flow to the penis, making it easier to get and keep an erection when sexually stimulated. They do not cause an erection automatically, so you still need to be sexually aroused for them to work.
There are four main PDE5 inhibitors, each available as a branded and a lower-cost generic version:
Sildenafil, the active ingredient in Viagra
Tadalafil, the active ingredient in Cialis
Vardenafil, the active ingredient in Levitra
Avanafil, the active ingredient in Spedra
Although these medicines work in a similar way, there are practical differences between them, including how quickly they start working, how long their effects can last, how food affects them and the doses available.
Some ED tablets can be supplied without a prescription following a pharmacist suitability check. These include Viagra Connect, Viagra Connect Melts, Aronix Tablets, Eropid Tablets, which all contain 50mg of sildenafil, and Avarante and Cialis Together, which contain 10mg tadalafil.
Other oral ED treatments at Quick Meds require a prescription and clinical assessment.
Daily and on-demand ED treatment
Most ED tablets are taken when needed before sex, but tadalafil is also available as a lower-dose daily treatment on prescription only.
On-demand ED tablets are taken before you plan to have sex. Sildenafil, vardenafil and avanafil are taken this way, while tadalafil can be used either on demand or daily.
Daily tadalafil is taken once a day, whether or not you plan to have sex, to provide ongoing effects. It may suit you if you have sex regularly or prefer more spontaneity.
Your prescriber can help you decide whether on-demand or daily treatment is more suitable based on your preferences, how often you have sex and your medical history.
Other erectile dysfunction treatments
If PDE5 inhibitor tablets are not suitable or don’t work well enough, other ED treatments include alprostadil medicines and vacuum pumps.
Alprostadil increases blood flow to the penis and is available in two forms. Vitaros is a cream applied to the opening of the penis, while Viridal Duo is given as an injection into the penis.
Vacuum pumps are placed over the penis to draw blood into it and create an erection. A constriction ring is then placed around the base of the penis to help maintain the erection.
A healthcare professional can help you decide which type of ED treatment may be suitable for you.
Request erectile dysfunction treatment online
Requesting erectile dysfunction treatment with QuickMeds is straightforward and does not need a face-to-face appointment:
Complete a short online consultation by answering a few questions about your health
Select the ED treatment you would like to request and complete your order.
Our prescriber reviews your request and checks that the treatment is suitable for you.
Eligible patients receive their ED medication in discreet packaging, with the option to reorder when needed.
Submitting an order is a request for treatment rather than a guaranteed prescription. If your chosen treatment is not suitable, we'll let you know and discuss appropriate next steps where possible.
Delivery information
Orders placed and approved before 3pm Monday to Friday are dispatched the same day, so you could receive your treatment as soon as the next working day, provided no further information is needed following your consultation.
All orders are sent in discreet packaging and delivered straight to your home or specified delivery address.
Option | Price | Delivery | Order by |
|---|---|---|---|
Tracked 48 | £5.99 | 2 to 3 working days | 3pm weekdays |
Tracked 24 | £7.99 | Usually next working day | 3pm weekdays |
Special Delivery | £10.95 | Guaranteed by 1pm next working day | 3pm weekdays |
Saturday Delivery | £12.95 | Guaranteed by 1pm Saturday | 3pm Friday |
Same Day (Birmingham only) | £25.00 | Same day, signature required | 3pm Mon to Fri |
What is erectile dysfunction?
Erectile dysfunction, also called impotence, is the difficulty getting or keeping an erection firm enough for sex. For some men, erectile dysfunction happens occasionally, often linked to tiredness, stress, or alcohol. For others, it is an ongoing problem.
Occasional difficulty is normal and not usually a concern, but if ED keeps happening, it is worth looking into the cause, because it can point to an underlying health condition.
Erectile dysfunction symptoms
The main erectile dysfunction symptom is the inability to get or maintain an erection for sex. This can range from:
Being unable to get an erection at all
Getting an erection that is not firm enough
Losing an erection before or during sex
Whether erections happen at other times can sometimes give a clue about the cause, but it cannot diagnose the cause on its own.
What causes erectile dysfunction?
Erectile dysfunction can have both physical and psychological causes – and sometimes a combination of the two.
Physical causes of ED include conditions that affect blood flow, nerves or hormone levels, such as:
High blood pressure
High cholesterol
Diabetes
Hormonal problems, including low testosterone
Being overweight
Smoking
Some medicines can also cause or contribute to erection problems.
Psychological causes include stress, anxiety, depression, relationship difficulties and anxiety about sex itself. These factors can affect erections even when there is no underlying physical problem that is stopping you from getting an erection.
If ED keeps happening, it is worth speaking to a healthcare professional. Erectile dysfunction can sometimes be associated with conditions affecting cardiovascular health. It’s worth getting recurring symptoms assessed rather than simply treating the erection problem.
Which erectile dysfunction treatment may be suitable for you?
There is no single erectile dysfunction medicine that is right for everyone. The table below can help you understand the practical differences to guide you towards which treatment you want to request.
It is not a substitute for a clinical assessment. The final choice is made with a prescriber.
Comparing the main erectile dysfunction pills
ED pills differ in how quickly they work, how long their effects last, how they are taken and whether or not they require a prescription.
ED medicine | Examples | Prescription needed? | When it starts working | How long it lasts | Things to consider |
|---|---|---|---|---|---|
Sildenafil | Viagra, generic sildenafil, Viagra Connect, Viagra Connect Melts, Aronix, Eropid | Yes – but some 50mg sildenafil tablets are available from pharmacies | Around 30–60 minutes | Around 4–6 hours | A high-fat meal can delay how quickly it works |
Tadalafil | Cialis, generic tadalafil, Cialis Daily, Cialis Together, Avarante | Yes – but some 10mg tadalafil tablets are available from pharmacies | Around 30–60 minutes | Up to 36 hours | Can be taken on demand or daily; food has little effect |
Vardenafil | Levitra, generic vardenafil | Yes | Around 30–60 minutes | Around 4–6 hours | May be less likely than sildenafil to cause changes in colour vision. |
Avanafil | Yes | Around 15–30 minutes | Up to 6 hours | Can start working sooner than some other ED tablets |
Your prescriber will recommend a suitable starting dose based on the ED medicine you choose, your health and any other medicines you take. It can sometimes take more than one attempt to find out how well a treatment works for you.
If one tablet does not work well or causes side effects, a prescriber may suggest increasing or reducing the dose, or trying another treatment.
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Who shouldn’t take ED medications?
Not every erectile dysfunction treatment is suitable for everyone. Which treatments you can use depends on your health, other medicines you take and the type of ED treatment.
ED tablets must not be taken with nitrate medicines used for chest pain because this can cause a dangerous drop in blood pressure. They may also be unsuitable if you have certain heart or blood pressure conditions or have recently had a heart attack or stroke.
ED creams and injections containing alprostadil may not be suitable if you have certain conditions that increase your risk of prolonged erections, such as sickle cell disease or leukaemia. Some conditions affecting the penis may also make these treatments unsuitable.
Tell your prescriber about any health conditions you have and all medicines you take so they can check which ED treatments are safe and suitable for you.
Do erectile dysfunction medications have side effects?
Like all medicines, erectile dysfunction treatments can cause side effects.
PDE5 inhibitor tablets such as sildenafil and tadalafil commonly cause:
Headache
Facial flushing
Blocked or runny nose
Indigestion
Dizziness
Depending on the specific medicine, some ED tablets can also cause other side effects. For example, sildenafil can cause changes to vision, while tadalafil can cause back pain and muscle aches.
Alprostadil creams and injections are more likely to cause side effects around the penis, such as penile pain, burning or irritation. Alprostadil injections can also cause bruising or bleeding where the medicine is injected.
All ED medicines can rarely cause a prolonged erection (priapism). Get urgent medical help if you have an erection lasting four hours or longer, as it can cause permanent damage if left untreated.
Always read the patient information leaflet supplied with your medicine for a full list of side effects.
Lifestyle changes that support erectile function
ED medication treats the symptom, but tackling the causes often improves ED and your wider health at the same time. Helpful changes include:
Keeping to a healthy weight and eating a balanced diet lower in fatty and salty foods.
Staying physically active, which supports blood flow and heart health.
Stopping smoking, which damages blood vessels.
Cutting down on alcohol and avoiding recreational drugs.
Managing stress and mental wellbeing, since anxiety and low mood can contribute to ED
Because ED can signal an underlying condition, it is also worth having any high blood pressure, cholesterol, or blood sugar checked and treated.
Why order ED treatments from Quick Meds?
QuickMeds provides a private, convenient way to request ED treatment online, with every request reviewed by a UK-registered prescriber.
If approved, your treatment is dispatched from our GPhC-registered pharmacy in plain, discreet packaging, with the option to re-order as needed. Our team is available to answer questions at any stage, and a prescriber can review your treatment if it is not working well or is causing side effects.
References
1. NHS. Erectile dysfunction (impotence). https://www.nhs.uk/conditions/erection-problems-erectile-dysfunction/
2. NICE Clinical Knowledge Summaries. Erectile dysfunction. https://cks.nice.org.uk/topics/erectile-dysfunction/
3. British National Formulary (BNF). Sildenafil. https://bnf.nice.org.uk/drugs/sildenafil/
4. British National Formulary (BNF). Tadalafil. https://bnf.nice.org.uk/drugs/tadalafil/
5. British National Formulary (BNF). Vardenafil. https://bnf.nice.org.uk/drugs/vardenafil/
6. British National Formulary (BNF). Avanafil. https://bnf.nice.org.uk/drugs/avanafil/
7. NHS. Sildenafil (Viagra). https://www.nhs.uk/medicines/sildenafil-viagra/
8. NHS. Tadalafil. https://www.nhs.uk/medicines/tadalafil/
9. NHS. Priapism (painful erections). https://www.nhs.uk/conditions/priapism/
10. Electronic Medicines Compendium (emc). Summaries of Product Characteristics for sildenafil, tadalafil, vardenafil and avanafil. https://www.medicines.org.uk/emc
11. European Association of Urology. EAU Guidelines on Sexual and Reproductive Health. https://uroweb.org/guidelines/sexual-and-reproductive-health
12. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994;151(1):54–61. https://pubmed.ncbi.nlm.nih.gov/8254833/
13. General Pharmaceutical Council. Check the register. https://www.pharmacyregulation.org/


















