Foundayo Tablets

Foundayo has received MHRA approval and you can now place your pre-order today for delivery when stock is available.

Foundayo is a new medication recently gaining MHRA approval for its use in type 2 diabetes and weight management. As with most other weight loss medications, it is a GLP-1 agonist designed to help people lose weight and lower blood sugar levels. It is available as an oral pill, which is taken once daily.

Foundayo at a glance

What Is Foundayo?

Orforglipron, or the branded Foundayo is a new weight loss medication formulated as a once-daily tablet. Developed by Eli Lilly, it belongs to the GLP-1 class of medications.

Unlike earlier GLP-1 treatments formulated as peptides, which require strict administration methods, Foundayo is a small-molecule non-peptide compound. Because of this, the tablet does not need any strict dietary restrictions, and can be taken with or without food, at any time of day - offering ease of administration.

How Does Foundayo Work?

As a GLP-1 agonist, orforglipron activates the natural GLP-1 (glucagon-like peptide-1) hormone. It acts on receptors in the brain and digestive system to regulate hunger by:

• Reducing food noise - by increasing the feeling of fullness, cravings and thoughts about food are reduced.

• Delaying stomach emptying - helping you feel fuller for longer after a meal.

• Regulating blood sugar levels - by stimulating insulin production when sugar levels are high

Who is Foundayo for?

Orforglipron is licensed for use in adults with:

• A body mass index (BMI) of 30 or above

• A BMI of 27 to 30 with a weight-related health condition such as high blood pressure or high cholesterol.

The treatment must be used alongside a reduced-calorie diet and increased physical activity levels.

Who should not take Foundayo?

Foundayo is not suitable for everyone. It should not be taken by:

• Anyone with a personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

• Anyone who is pregnant or breast-feeding

• Patients who are allergic to orforglipron or any of its ingredients.

Request Foundayo private prescription online

A Foundayo prescription can be requested online through Quick Meds. Simply complete a short consultation form, which our clinicians will review to assess your suitability. If you're eligible, you'll have a telephone consultation with the prescriber, after which your Foundayo will be delivered directly to your door.

How to take Foundayo?

Foundayo is available as a tablet, taken once everyday. Due to the way it is formulated as a small-molecule, it offers greater flexibility over other oral GLP-1 treatments, which require strict fasting rules.

The new Foundayo tablet:

• Can be taken at any time of day.

• Can be taken with or without food.

• Can be taken with any liquid, without restriction on water volume.

• Tablets must be swallowed whole, do not cut, crush, chew or disperse them.

Foundayo doses and dosing schedule

Foundayo tablets are available in 6 strengths: 0.8mg, 2.5mg, 5.5mg, 9mg, 14.5mg, and 17.2mg. Patients new to treatment must start at the initiation dose of 0.8mg once daily. This is taken for 30 days before increasing to the next highest dose. This process allows the body to adjust to treatment safely, minimising the risk of side effects.

What if I miss a dose?

If you miss a dose of Orforglipron:

• Take it as soon as you remember - do not take more than one tablet per day

• If it is almost time for your next scheduled dose, skip the missed dose and take your next dose at the usual time

• Do not take an extra dose to make up for a missed one

• If you have missed taking Orforglipron for 7 days or more, contact your prescriber

If you are unsure about what to do after missing a dose, give us a call on 0121 628 5318, email or send us a message or contact us via the form on our website.

How does Foundayo compare to other weight-loss treatments?

Founday vs Mounjaro

Foundayo is a GLP- 1 agonist and offers a needle-free convenient option. Mounjaro has a dual-receptor action as it works on both GLP-1 and GIP receptors. Foundayo is taken as a tablet daily whilst Mounjaro is taken as a once weekly injection. Click here to our full blog on Foundayo vs Mounjaro

Foundayo vs Wegovy injection

Both are GLP-1 agonists but Foundayo offers effectiveness without the need for refrigeration or injection. Wegovy injections are taken once weekly

Foundayo vs Wegovy tablets

Foundayo 36mg tablets led to an average weight loss of 12.4% over a 72 week period in the ATTAIN-1 trial whereas Wegovy 25mg tablets achieved 16.4% over 64 weeks in the OASIS 4 trial. Unlike Wegovy tablets which must be taken on an empty stomach, followed by a 30 minute waiting period for food/drink, Foundayo can be taken without any dietary restrictions.

Summary table

What are Foundayo (Orforglipron) side effects?

As with all medication, Foundayo can cause side effects, though not everyone gets them. In line with other GLP-1 agonists, most side effects involve the digestive system, especially when starting treatment or increasing the dose.

Foundayo interactions with other medications

Let your provider know if you are taking any other medications. Foundayo may interact with certain medications and may require dose changes or are best avoided.

Medications such as clarithromycin and ketoconazole can slow down how your liver breaks down Foundayo. This may lead to higher levels of Foundayo in your blood which could increase the risk of side effects. Medications such as carbamazepine or rifampicin can speed up how your liver processes Foundayo. This can lower the level of Foundayo in your blood making it less effective.

Speak to our clinicians as they will be able to advise you on which dose of Foundayo is suitable for you.

Foundayo can affect how well your body processes other medications:

• Simvastatin: Foundayo can increase the amount of simvastatin in your blood, therefore it is advised that the dose simvastatin should not exceed 20mg daily while on treatment.

• Oral contraceptive pills: Delayed gastric emptying may affect the absorption of oral medications, advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 30 days after initiation with Foundayo and for 30 days after each dose escalation

Foundayo (Orforglipron) trials and efficiency

In the ATTAIN-1 phase 3 trial, over a 72-week period:

• Participants taking the highest orforglipron dose achieved an average weight loss of 12.4% compared to 0.9% in the placebo group.

• 60% of participants lost 10% of their initial body weight, whilst 40% of participants lost 15%

In addition to weight loss marker, the medication led to significant improvements in cardiovascular risk factors, including:

• Average of 11.1cm reduction in waist circumference.

• 21.6% reduction in triglycerides.

• 47.7% reduction in high-sensitivity C-reactive protein (hsCRP) - a marker of inflammation.

ATTAIN-2 assessed those managing weight and type 2 diabetes. This trial demonstrated a 10.5% average weight loss along with a 1.8% point reduction in HbA1c levels.

ATTAIN-MAINTAIN - confirms Foundayo’s long-term safety profile and its ability to help patients maintain their weight loss over extended periods.

How to support your weight loss while taking

Orforglipron is an effective weight management solution, but ideal results which last depend on incorporating sustainable lifestyle changes:

• Prioritise protein. A reduced appetite can lower food intake. Aim for higher protein meals to preserve lean muscle mass.

• Stay hydrated. Consistent hydration reduces the risk of side effects and dehydration-related kidney problems.

• Resistance exercise. Combine treatment with strength training to preserve metabolism.

• Fibre. Increased fibre intake can help prevent constipation.

Why Choose Quick Meds for GLP-1 Weight Loss Treatments?

Quick Meds provides a safe, discreet and regulated UK healthcare service, all from the comfort of your own home:

• GPhC Regulated. Fully licensed UK pharmacy operating under strict clinical standard.

• Expert Clinical Oversight. Every medication request is required by qualified UK based prescribers, specialising in weight management.

• Discreet Delivery. Fast, tracked UK delivery in plain packaging, to protect your privacy.

How will Orforglipron be prescribed at Quick Meds once available?

Accessing Foundayo from Quickmeds is streamlined in the following process:

• Online Consultation - complete an online consultation which asks about your weight, medical history and if you take other medication.

• Clinical Review - A UK-registered prescriber reviews your profile, ensuring clinical safety.

• Prescription Approval - Once approved, a prescription is generated within our GPhC-registered pharmacy.

• Dispensing & Delivery - Once dispensed, all orders are packaged securely in plain, discreet packaging and delivered through tracked methods straight to your door.