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At a glance: What is Nevolat?
Nevolat is a prescription weight loss treatment that contains the active ingredient liraglutide. It is licensed for patients looking to lose weight who meet the BMI (body mass index) criteria. To work effectively, Nevolat must be used alongside a calorie controlled diet and exercise plan to be effective.
Liraglutide mimics GLP-1, the naturally occurring hormone released after eating. In doing do, it can control appetite, reduce hunger and help you lose weight. Suitable for adults with obesity or adults who are overweight but also have a weight related health condition.
Nevolat should only be used under medical supervision, with regular monitoring required for side effects and to ensure it works effectively.
Product Summary Table
Feature | Details |
|---|---|
Brand Name | Nevolat |
Active Ingredient | Liraglutide |
Strengths Available | 6 mg/ml in pre-filled injection pens (up to 3.0 mg once daily) |
How it Works | Mimics a naturally occurring hormone (GLP-1) to regulate appetite and food intake |
Administration | Daily subcutaneous injection |
Injection Sites | Abdomen, thigh, or upper arm (rotate sites daily) |
Starting Dose | 0.6 mg once daily, increased weekly |
Maximum Maintenance Dose | 3.0 mg once daily (if tolerated and prescribed) |
Storage | Store in the fridge (2–8°C) before first use; keep below 30°C after opening |
Prescription Required | Yes, only available after a clinical consultation |
Suitable For | Adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related conditions |
Not Suitable For | People with certain thyroid diseases, severe kidney or heart failure, or those who are pregnant or breastfeeding |
Common Side Effects | Nausea, vomiting, constipation, diarrhoea, headache |
Manufacturer | Zentiva |
Regulatory Status | Prescription-only medicine, regulated in the UK |
Who can use Nevolat?
Nevolat weight loss injections can be used by adults who meet the BMI criteria. BMI is calculated using a patients initial body weight and height, and calculating a ratio.
Nevolat is indicated for weight management for adults with a BMI or 30 (obesity) or between 27 and 30 (overweight) and with a weight related medical condition. This could be diabetes, pre-diabetes, high blood pressure, dyslipidaemia or obstructive sleep apnoea.
Before considering any weight loss treatment it is important to speak to your healthcare provider, particularly if you take other medications or have a history of other medical conditions. When completing a prescription request online, before issuing a prescribed treatment, your provider will assess your medical history to determine eligibility.
How does Nevolat work to support weight loss?
Nevolat works by mimicking the actions of a naturally occurring hormone in the body, glucagon like peptide-1 or GLP-1. By activating this hormone, it can take longer for the body to digest food which can also stay in the stomach for longer, leading to feelings of early fullness.
This early fullness feeling can help reduce calorie intake which can help inform better eating habits and avoid overeating. Many of us have been socially conditioned to eat 3 square meals a day which are generally highly processed and high in calories.
This treatment helps take eating back to basics, relying on your body's food noise and only eating if you really need to (i.e. in response to hunger). This can help avoid overeating and help to maintain a healthier body weight when you decide to come off the treatment.
How to use Nevolat: pen, dose and schedule
Where and how to inject
Nevolat is a once daily weight loss injection, injected under the skin, usually into the stomach, upper thigh or upper arm. It can be taken at any time of day, with or without food though it should be injected around the same time each day. The injection sites should be rotated to reduce the risk of injection site reactions.
Nevolat comes in a pre-filled pen designed for easy self-injection. To use, follow the below steps:
Wash your hands thoroughly
Remove the outer cap and attach a new needle to the pen
Check the solution - it should be clear and colourless. Do not use if cloudy or contains particles
Select your injection site and gently clean with an alcohol wipe
Prepare the Nevolat pen by rotating the dose counter to the correct dose
Remove the inner needle cap
Inject under the skin at a 90-degree angle
Hold the Nevolat pen in place for a few seconds to ensure the full dose has been delivered
Safely remove the used needle and dispose in a sharps container
Replace the cap and store appropriately
The dose counter shows each individual dose that can be injected, 0.6mg, 1.2mg, 1.8mg, 2.4mg and 3mg, making it easier to inject.
Dosing Plan
Nevolat weight loss treatment starts at a low dose which is gradually increased over the first five weeks of treatment. Using the treatment in this way, reduces the risk of gastric side effects, allowing the body to gradually adjust to the treatment.
Week 1 - 0.6mg once daily
Week 2 - 1.2mg once daily
Week 3 - 1.8mg once daily
Week 4 - 2.4mg once daily
Week 5 onwards - 3mg once daily. This is the maintenance dose which you would then remain on for the remaining duration of your treatment. Do not inject Nevolat at any dose higher than 3mg once daily.
Missed or double doses
In the case of a missed dose, if it is remembered within 12 hours from when you usually inject, use as soon as you remember. However, if more than 12 hours have passed since you should have used Nevolat, you should skip the dose missed and inject your next dose the following day at the usual time.
Do not take an extra dose to make up for a dose thats missed. If too much Nevolat is taken, you should talk to a Dr or go to hospital. Double dosing could increase the risk of side effects, such as nausea, vomiting or low blood sugar.
How much weight could I lose with Nevolat?
Clinical trials show an average loss of 5-9% after 6-12 months of using the Nevolat weight loss injections alongside changes a balanced diet and exercise. This is greater than the small weight loss seen with placebo - between 2-3%.
Importantly, individual results can vary. This depends on a patients starting body weight and how consistent they are with both the treatment and adjustments to lifestyle changes.
What to eat and how to move while using Nevolat
Whilst a proven treatment, Nevolat works best when used alongside a healthy diet and regular physical activity. The treatment helps control appetite but long term sustainable weight loss depends on maintaining sustainable habits.
Following a balanced calorie controlled diet which focuses on whole foods and whole grains can help aid weight loss. Try to limit intake of high-fat and sugary foods and eat smaller, regular meals.
Regular meals, as opposed to skipping meals can help maintain energy levels throughout the day. Additionally, drink plenty of water which can help the treatment work better but also reduce the risk of side effects such as nausea or constipation.
In addition to this, increasing physical activity can help you burn more calories, tapping into your energy stores. There's benefit to all different types of workouts - focusing on consistency and gradually increasing the time of each session can help build a sustainable lifestyle which works alongside the daily injection.
Whilst you can drink alcohol whilst on Nevolat, it is important to limit intake to within national guidelines. The NHS recommends no more than 14 units of alcohol per week, spread over 3 or more days. Excess alcohol consumption can increase the risk of severe side effects such as pancreatitis.
Side effects and safety
Common side effects
Like all medicines, Nevolat can cause side effects. The most common are nausea, constipation, tiredness, or a mild stomach upset.
Nausea can be managed by eating smaller, more frequent meals, taking regular sips of a cold drink or consuming ginger or peppermint symptoms. Weight loss treatments tend to cause nausea if more calories are consumed than are required or if you consume too many sugary or carb-heavy foods.
Serious but rare side effects
More serious side effects of Nevolat include pancreatitis or an allergic reaction.
If whilst on the Nevolat weight loss injections, you experience severe stomach pain which travels along your back, alongside nausea/sickness or a fever, you should stop treatment and seek immediate medical attention - this is a sign of pancreatitis.
Anaphylaxis or a severe allergic reaction is rare. If you experience swelling of the face, tongue or throat, difficulty breathing or a severe rash or dizziness, stop the treatment and seek emergency medical attention.
Whilst nausea is a common side effect, prolonged nausea can lead to dehydration, particularly upon first starting the treatment. for this reason its important to drink plenty of water
Who should not use Nevolat
Whilst Nevolat can be prescribed safely to most individuals, it may not be appropriate for everyone. Patients with pre-existing medical conditons should be reviewed carefully by a prescriber as there are circumstances where Nevolat is contraindicated and should be avoided.
Nevolat should not be used in individuals with severe kidney or liver disease, as clinical experience in these groups is limited. In cases of mild to moderate kidney disease, treatment may be considered, but maintaining adequate hydration is essential to minimise the risk of complications.
For those with thyroid disease, treatment may be possible but should first be carefully assessed by a healthcare professional. Clinical studies in rodents have shown a risk of thyroid C-cell tumours, including medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia type 2 (MEN2) - a type of thyroid cancer. Although the relevance to humans remains unproven, Nevolat should be avoided in patients with a personal or family history of MTC or MEN2.
Like other weight loss medications, Nevolat has been associated with cases of acute pancreatitis - a medical emergency. Patients with a history of pancreatitis should be treated with caution, and therapy should be discontinued immediately if pancreatitis is suspected.
As rapid or significant weight loss can increase the risk of gallstone formation, patients who develop upper stomach pain with severe nausea suggestive of gallstones whilst on Nevolat treatment should stop and seek medical advice.
Nevolat is contraindicated in patients who are pregnant, as it may harm an unborn baby. It is also not recommended while breastfeeding, as it is unknown whether the medication is excreted in breast milk.
There is no clinical experience in patients with heart failure and therefore Nevolat is nor recommended for use in these patients.
Nevolat vs other weight loss treatments
Feature | Nevolat | Wegovy | Mounjaro |
|---|---|---|---|
Active ingredient | Liraglutide | Semaglutide | Tirzepatide |
Class | GLP-1 receptor agonist | GLP-1 receptor agonist | Dual GIP (glucose dependent insulinotropic polypeptide) and GLP-1 receptor agonist |
How it helps with weight loss | Acts like a natural hormone that helps control appetite, reducing food intake | Same mechanism as liraglutide with longer action that supports appetite control and reduced intake | Targets two hormones involved in appetite and blood sugar control which can reduce hunger and help you feel fuller for longer |
How often you take it | Daily injection | Weekly injection | Weekly injection |
Typical dose titration | Start 0.6 mg daily, increase weekly | Start low, increase every 4 weeks in response to tolerance | Start low, increase every 4 weeks in response to tolerance |
Typical maintenance dose used for weight management | Up to 3.0 mg once daily if prescribed | Up to 2.4 mg once weekly if prescribed | Up to 15 mg once weekly if prescribed |
Where to inject | Abdomen, thigh or upper arm. Rotate sites | Abdomen, thigh or arm. Rotate sites | Abdomen, thigh or arm. Rotate sites |
Storage | Keep pens refrigerated before first use. In use, follow the leaflet guidance on room temperature limits and expiry | Similar refrigerated storage before first use. Follow in-use guidance in the leaflet | Similar refrigerated storage before first use. Follow in-use guidance in the leaflet |
Who it may suit | People who prefer a daily routine and want gradual, structured dose increases | People who prefer once-weekly dosing and longer-acting appetite control | People who want once-weekly dosing and a medicine that acts on two pathways. Dose options can help tailor treatment to those wanting to maintain at a lower dose. |
Common side effects | Nausea, vomiting, diarrhoea or constipation, headache. Often settle as your body adjusts | Similar stomach-related effects. Usually improve with slow dose increases | Similar stomach-related effects. Some people may also report fatigue or reduced appetite |
Important cautions | Not suitable for everyone including some thyroid conditions, severe kidney disease, severe heart failure, or past pancreatitis. Not for pregnancy or breastfeeding | Similar cautions. Always discuss your medical history and medicines with a clinician | Similar cautions. Always discuss your medical history and medicines with a clinician |
Prescription and assessment | Prescription only following a clinical assessment | Prescription only following a clinical assessment | Prescription only following a clinical assessment |
Good to know | Works best with a reduced-calorie diet and physical activity. Daily routine can help some people stay on track | Weekly schedule may be more convenient for some people | Dual-pathway action may be helpful for some people under clinician guidance |
Practical buying and regulation guidance in the UK
At Quick Meds, your safety is our top priority, and we operate under strict regulatory standards.
Every new patient completes a telephone consultation to discuss their starting weight, weight loss journey, and receive personalised diet and exercise guidance to help maximise treatment outcomes safely.
All orders are clinically reviewed by a qualified prescriber before approval.
Prescriptions are dispensed and packed under pharmacy supervision, with full data protection compliance.
All medicines are sourced directly from the manufacturer, in line with MHRA regulations.
Purchasing from unregulated websites can be unsafe, as medicines may be counterfeit or unlicensed. Warning signs include:
No UK address, registration number, or named pharmacist
No consultation or health assessment required
Unrealistic prices or offers for bulk purchases without review
Always ensure an online pharmacy displays the GPhC pharmacy logo, which links to their official registration details.
Storage, travel and handling
Before first use, Nevolat pens should be kept in the refrigerator, between 2°C–8°C. Do not freeze the pens and discard if they have been frozen. It is recommended to store in the original carton to protect from light.
After first use, the pen can be kept in the fridge or at room temperature as long as the temperature does not exceed 30°C. Always replace the cap after each use to protect from light. The pens have an in use shelf life of 30 days, after which, any remaining solution must be discarded.
When travelling, keep pens in a cool, insulated pouch away from direct sunlight and heat. Carry the medication with needles in your hand luggage and not in your checked bag. Temperatures in the baggage hold of aicraft may drop below freezing, affecting the medication.
Carry a copy of your prescription or treatment letter for ease through airport security and we would always encourage patients to check with their travel agent for any additional requirements, either during travel or at your destination.
Nevolat at Quick Meds
You may be able to buy Nevolat online following an online consultation subject to clinician approval. As a prescription only treatment, a clinician must review your health, your body weight at initiation, and alternative weight loss treatments you may have already tried to ensure Nevolat is the most appropriate choice for you.
At Quick Meds, to place an order:
Complete an online consultation form and pay for an order online
Clinicians will contact you for a telephone consultation, may request additional information and offer personalised advice
Your order will be approved by the prescribing team, dispensed and packed appropriately and sent to your UK-based address.
The care doesn't stop there. Our team of clinicians are at hand to offer any help that is required throughout your weight loss journey. Alternatively, if Nevolat is not suitable, we can offer advice on a different weight loss injection which may be more appropriate.
For those nervous about using an injection, weight loss tablets may be an option. At present, the only oral weight loss treatment available is Orlistat, which reduces the absorption of dietary fat.
Frequently Asked Questions
Everything you need to know
What is the starting and maximum dose?+−
The starting dose of Nevolat is 0.6mg once daily, increasing up to a maximum dose over 5 weeks to 3mg once daily.
What is Nevolat and how does it work?+−
Nevolat is a weight loss medication. A once-a-day injection, clinical trials have proven Nevolat is an effective treatment for those looking to lose weight when used alongside a balanced diet and increased exercise.
What’s the difference between Nevolat and Saxenda?+−
The difference between Nevolat and Saxenda is the branding. Saxenda is the original branded product. Nevolat is a non-branded version containing the same active ingredient. Both treatments work in the exact same way yet Nevolat is more affordable.
What if I miss a dose?+−
If you miss a dose and is remembered within 12 hours, use as soon as you remember. If more than 12 hours have passed, you should skip the missed dose and inject your next dose the following day at the usual time.
When will I start to notice weight loss?+−
You can start to notice weight loss within the first few weeks, though individual results can vary. Ultimately, adherence to a healthy diet and increased exercise can significantly impact your rate of weight loss
Can I drink alcohol while using it?+−
Yes, you can drink alcohol whilst on Nevolat though it is important to drink within moderation. Excess alcohol and the medicine itself are risk factors for pancreatitis - a medical emergency.
Additionally, many alcoholic beverages contain excess calories, which can affect your weight loss results.
Can Nevolat cause low blood sugar?+−
Yes Nevolat can cause low blood sugar, though this is more likely if used alongside diabetes medication.
What if I experience nausea or stomach pain?+−
Mild nausea or stomach pain is common with Nevolat treatment and should resolve on its own after the first few weeks of treatment. If however, symptoms persist or get worse, stop using the treatment and speak to your provider. In an emergency, always call 999.
How long can I use Nevolat for?+−
Nevolat is intended for long-term use as part of a weight management plan. There is no fixed maximum duration but ongoing treatment should be regularly reviewed to balance out risks to benefit.
Can I stop and restart the treatment later?+−
Nevolat can be stopped at any time but its important to do so gradually, under medical supervision. This reduces the risk of weight gain caused by a sudden return in appetite.
To restart, a new clinical review is needed. You may need to start back at the lower dose and be titrated up again, to minimise side effects.
