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Viridal Duo

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Viridal Duo

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Buy Viridal Duo online in the UK

What is Viridal Duo?

Viridal Duo is a prescription only treatment containing alprostadil. As an injectable, it is administered directly into the penis to help with erectile dysfunction.

Alprostadil improves blood flow to the penis which can help achieve and maintain an erection.

Before using the Viridal Duo starter pack, a medical professional must show you how to use the injections. You need this training before you can use them at home.

Viridal Duo is available in 3 strengths, 10mg, 20mg and 40mg and comes in a glass cartridge with two chambers:

  • One contains alprostadil, the drug

  • The other contains sodium chloride solution.

When combined, they create an injection-ready solution for intracavernosal injection (injecting into the shaft of the penis).

How does Viridal work?

The alprostadil injection works as a vasodilator, i.e it opens blood vessels, increasing blood flow into the spongy tissue of the penis, where it is held, leading to an erection.

Erections happen because of blood flow. The blood vessels in the penis need to expand and let in more blood to cause and maintain an erection.

Unlike common ED tablets, such as sildenafil (Viagra) or tadalafil (Cialis), sexual stimulation is not required for Viridal Duo to work.

The erection process

The penis's blood vessels enlarge and fill with blood when a man is sexually aroused due to nerve signals. This causes the penis to become hard by filling the corpora cavernosa, two chambers in the penis.

Health of blood vessels

The blood arteries must be healthy and able to transport enough blood for this process to function. A restricted flow of blood or injury to the blood vessels might make it difficult to achieve or sustain an erection.

How effective is Viridal Duo

Viridal Duo has shown a high level of effectiveness. Clinical trial data over a six-month study shows men were able to engage in sexual activity after 94% of injections.

87% of men reported a “satisfactory” experience after using the treatment, which proved effective regardless of the underlying cause of ED.

The data shows, due to its local administration directly to the penis, Viridal Duo offers an advantage over traditional oral treatments in that

  • It does not require patients to be sexually stimulated to work

  • It works regardless of the cause - particularly useful for men who suffer from psychological ED.

How to use Viridal Duo

Before starting treatment at home, it's important to have a thorough consultation with a healthcare professional who can show you how to use it and determine the safest starting dose for you.

The injection should be administered into the shaft of the penis at least 10-15 minutes before anticipated sexual activity. Sexual stimulation is not required. You shouldn’t use Viridal more than once in 24 hours or more frequently than 2-3 times a week. If you use more than you should, this runs the risk of severe side effects.

Always double check the dose you are taking and follow the instructions given to you by your prescribing clinician. Most men need 10 to 20 micrograms for each injection. Always follow your clinicians dosage instructions on the label. You must not use more than 40 micrograms in one injection.

How to inject

The packaging contains the Easy-duo injector, injection needles and the Viridal cartridge which contains the drug and saline. Ensure to check the injector for damage and ensure you have the correct dose vial prior to use.

To inject:

  1. Prepare the needle - remove its seal and attach it to the injector, twisting to tighten

  2. Prepare the cartridge - clean the cartridge tip with an alcohol swab then insert into the injector by unscrewing the plunger. Screw the plunger back on.

  3. Mix the solution - pointing the injector up, push the plunger until the grey stoppers meet then shake gently until the solution becomes clear.

  4. Remove air bubbles - tap the injector vigorously to bring bubbles to the top then push the plunger to release a drop of solution.

  5. Set the dose - move the plunger upward until the grey stopper has reached the prescribed dose.

  6. Prepare the injection site - clean and let dry.

  7. Inject the dose - hold level and inject needle straight into injection site. Slowly inject the dose over 5-10 seconds.

  8. After injecting - Remove the needle. Apple pressure to site if bleeding occurs

  9. Wait for erection - It should occur within 5-15 mins.

Full usage instructions can be found on the manufacturer's patient information leaflet including with the medication.

The erection should last for one hour. If it lasts between 2-4 hours, contact your clinician and if it lasts for longer than 4 hours, seek immediate medical attention.

Side effects

As with any medication, Viridal can cause side effects though not everyone gets them. In clinical trials, 50% of men experienced pain in the penis, though this was mild.

Other common side effects include:

  • Burning sensation during injection

  • Pain at the injection site

  • Lumps at the injection site or in your penis after long-term use

  • Spot-like bruising (blood spots under the skin) at the injection site

  • A fluttering sensation due to uncontrollable muscle movement

  • Erections might occur more often and longer in duration

  • Bend or kink in the penis, especially after long-term use

Seek immediate medical attention if you experience any of the following:

  • A painful erection lasting more than 4 hours

  • Serious allergic reactions which cause difficulty in breathing or dizziness

  • Skin reactions such as rashes and blistering

For a full list of side effects, please read the patient information leaflet.

Who should not use Viridal Duo?

Do not use Viridal Duo if you:

  • Are allergic to alprostadil or any of the other ingredients in Viridal Duo.

  • Have a penile implant

  • Have recently had a heart attack/stroke and been advised not to have sex

  • Have a condition that makes you more susceptible to developing priapism such as:

    • Sickle cell anaemia

    • Leukaemia (blood cancer)

    • Multiple myeloma (bone cancer)

  • Have scarring or deformity of the penis (angulation, cavernosal fibrosis)

The injection should not be used alongside other ED treatments such as PDE-5 tablets (sildenafil, tadalafil).

Before using Viridal Duo, it's crucial to inform the doctor about all of your medical history and all the medications you are currently taking to ensure the treatment is safe for you.

How long does Viridal Duo last?

An erection can occur 10 to 15 minutes after injecting Viridal Duo into the penis and usually lasts for about one hour.

If the erection lasts for between 2-4 hours, speak to your clinician as your dose may need to be adjusted.

If it lasts for more than 4 hours, seek immediate medical attention - go to hospital right away.

Is Viridal Duo right for me?

Viridal Duo injections are indicated for use by men over 18 who suffer from erectile dysfunction. They must not be used by women, children or the elderly (over 80 years).

If you haven't tried any treatments for erectile dysfunction, we recommend starting with one of our first-line treatments, such as: Viagra (Sildenafil) Cialis (Tadalafil), Spedra or vardenafil.

If you cannot take tablets for any reason, topical treatments may be better suited such as Vitaros cream. This contains the same active ingredient as Viridal Duo (alprostadil) and is applied directly to the penis opening.

If you take other medications, you should check suitability with a healthcare provider. Viridal Duo can interact with common painkillers such as ibuprofen, blood thinners and antidepressants.

How to buy Viridal online from Quick Meds?

Simple, secure online consultation

You can buy Viridal from our clinic at Quick Meds. As a prescription only medication, you need to complete an online questionnaire before purchasing. This asks about your symptoms, your medical history and if you are taking any other medication.

Our UK registered prescribers review the form to ensure the treatment is safe before approving.

Importantly, patients must have been shown how to use the injection by a healthcare provider. This will be assessed during the consultation process.

UK regulated pharmacy dispensing and delivery

As a GPhC registered pharmacy, Quick Meds offers evidence based advice and treatments which are regulated by the MHRA.

As part of the regulatory requirements, each private prescription issued is reviewed by pharmacists and prescribers trained to provide the highest standard of service.

Once approved, we pack your product using discreet packaging and deliver to most UK based addresses using tracked delivery methods. We offer delivery options as soon as by the next working day following approval.

Frequently Asked Questions

Everything you need to know

Are injections better than pills for treating ED?
+−

The decision between tablets and injections is a personal one. Injectable treatments do not require sexual stimulation to work like tablets do. Additionally, drug absorption difficulties that may arise with some tablets are also resolved by injectables.

However, the injection requires a technique which is not as simple as swallowing a tablet.

Do you need sexual stimulation with Viridal Duo?
+−

No, Viridal injections help you to produce an erection without sexual stimulation required.

How often can I take Viridal Duo?
+−

Viridal Duo must be injected once a day maximum and should not be used more than three times a week.

How long does an erection last with Viridal?
+−

An erection should last up to 1 hour. If it lasts between 2-4 hours, contact your clinician and if it lasts for longer than 4 hours, seek immediate medical attention.

How quickly does Viridal lead to an erection?
+−

Viridal starts to work immediately and can help achieve an erection within 5-15 minutes. 

What if Viridal Duo does not work?
+−

Speak to your clinician who can safely adjust the dose. Do not adjust the dose without speaking to a healthcare professional first.

Do Viridal Duo injections hurt?
+−

The injection does not generally hurt though some may experience some slight discomfort upon injecting or a sharp scratch when the needle is inserted. 

Are Viridal Duo injections available on the NHS?
+−

Viridal Duo injections are available on the NHS but access is restricted to patients who meet a set criteria.

Are there alternatives to Viridal Duo?
+−

Yes, the active ingredient alprostadil is also available as a cream called Vitaros.


Additionally, there are numerous well-known tablets available such as Viagra or Cialis.

Can I use Viridal Duo alongside Viagra or Cialis?
+−

No, you should not combine treatments. Using them together significantly increases the risk of serious side effects, such as priapism - a painful, long-lasting erection.

Written by

AAdnan Jalil

Adnan Jalil

MPharm, GDL, IP, AHA

Clinical IP Pharmacist

View profile →

Reviewed by

WWajahet Bhatti

Wajahet Bhatti

MPham, IPrescMaster of Pharmacy

Clinical Governance Pharmacist

View profile →